Ataxin-3 (ATXN3) Rabbit mAb, Unconjugated, Monoclonal
Catalog Number:
ABB-A22094
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| Article Name: | Ataxin-3 (ATXN3) Rabbit mAb, Unconjugated, Monoclonal |
| Biozol Catalog Number: | ABB-A22094 |
| Supplier Catalog Number: | A22094 |
| Alternative Catalog Number: | ABB-A22094-100UL,ABB-A22094-20UL |
| Manufacturer: | ABclonal |
| Host: | Rabbit |
| Category: | Antikörper |
| Application: | ELISA, WB |
| Species Reactivity: | Human |
| Immunogen: | Recombinant protein (or fragment).This information is considered to be commercially sensitive. |
| Conjugation: | Unconjugated |
| Alternative Names: | AT3, JOS, MJD, ATX3, MJD1, SCA3, Ataxin-3 (ATXN3) |
| Machado-Joseph disease, also known as spinocerebellar ataxia-3, is an autosomal dominant neurologic disorder. The protein encoded by this gene contains (CAG)n repeats in the coding region, and the expansion of these repeats from the normal 12-44 to 52-86 is one cause of Machado-Joseph disease. There is a negative correlation between the age of onset and CAG repeat numbers. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. |
| Application Dilute: | WB,1:1000 - 1:5000|ELISA,Recommended starting concentration is 1 µg/mL. Please optimize the concentration based on your specific assay requirements. |
| Application Notes: | Cross-Reactivity: Mouse,Rat. ResearchArea: Epigenetics Nuclear Signaling,Cell Biology Developmental Biology,Ubiquitin,Neuroscience,Neurodegenerative Diseases. Shipping: Ice Bag |
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Western blot analysis of extracts from various lysates, using Ataxin-3 (ATXN3) antibody (A22094) at 1:2000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution. Lysates/proteins: 25µg per lane.Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 30s. |
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