GDF15 Rabbit mAb, Unconjugated, Monoclonal
Catalog Number:
ABB-A22097
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| Article Name: | GDF15 Rabbit mAb, Unconjugated, Monoclonal |
| Biozol Catalog Number: | ABB-A22097 |
| Supplier Catalog Number: | A22097 |
| Alternative Catalog Number: | ABB-A22097-100UL,ABB-A22097-20UL |
| Manufacturer: | ABclonal |
| Host: | Rabbit |
| Category: | Antikörper |
| Application: | ELISA, WB |
| Species Reactivity: | Human |
| Immunogen: | Synthetic peptide. This information is considered to be commercially sensitive. |
| Conjugation: | Unconjugated |
| Alternative Names: | PDF, MIC1, PLAB, MIC-1, NAG-1, PTGFB, GDF-15, GDF15 |
| This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. The protein is expressed in a broad range of cell types, acts as a pleiotropic cytokine and is involved in the stress response program of cells after cellular injury. Increased protein levels are associated with disease states such as tissue hypoxia, inflammation, acute injury and oxidative stress. |
| Application Dilute: | WB,1:2000 - 1:8000|ELISA,Recommended starting concentration is 1 µg/mL. Please optimize the concentration based on your specific assay requirements. |
| Application Notes: | Cross-Reactivity: Human. ResearchArea: Signal Transduction,Cell Biology Developmental Biology,Cell Cycle,Cytoskeleton,Extracellular Matrix,Bone,Growth factors,Immunology Inflammation,Cytokines,Cardiovascular,Heart,Hypertrophy. Shipping: Ice Bag |
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Western blot analysis of various lysates using GDF15 Rabbit mAb (A22097) at 1:2000 dilutionincubated overnight at 4°C. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Negative control (NC): Ramos Exposure time: 10s. |
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