DDR1/MCK10/CD167a Rabbit mAb, Unconjugated, Monoclonal
Catalog Number:
ABB-A22705
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| Article Name: | DDR1/MCK10/CD167a Rabbit mAb, Unconjugated, Monoclonal |
| Biozol Catalog Number: | ABB-A22705 |
| Supplier Catalog Number: | A22705 |
| Alternative Catalog Number: | ABB-A22705-100UL,ABB-A22705-20UL |
| Manufacturer: | ABclonal |
| Host: | Rabbit |
| Category: | Antikörper |
| Application: | ELISA, WB |
| Species Reactivity: | Human |
| Immunogen: | Recombinant protein (or fragment).This information is considered to be commercially sensitive. |
| Conjugation: | Unconjugated |
| Alternative Names: | CAK, DDR, NEP, HGK2, PTK3, RTK6, TRKE, CD167, EDDR1, MCK10, NTRK4, PTK3A, DDR1/MCK10/CD167a |
| Receptor tyrosine kinases play a key role in the communication of cells with their microenvironment. These kinases are involved in the regulation of cell growth, differentiation and metabolism. The protein encoded by this gene belongs to a subfamily of tyrosine kinase receptors with homology to Dictyostelium discoideum protein discoidin I in their extracellular domain, and that are activated by various types of collagen. Expression of this protein is restricted to epithelial cells, particularly in the kidney, lung, gastrointestinal tract, and brain. In addition, it has been shown to be significantly overexpressed in several human tumors. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. |
| Application Dilute: | WB,1:1000 - 1:2000|ELISA,Recommended starting concentration is 1 µg/mL. Please optimize the concentration based on your specific assay requirements. |
| Application Notes: | Cross-Reactivity: Mouse,Rat. ResearchArea: Protein phosphorylation,Cancer,Signal Transduction,Kinase,Tyrosine kinases,Immunology Inflammation,CDs,Neuroscience,Cardiovascular,Heart,Cardiogenesis. Shipping: Ice Bag |
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Western blot analysis of various lysates using DDR1/MCK10/CD167a Rabbit mAb (A22705) at 1:1000 dilutionincubated at room temperature for 1.5 hours. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Negative control (NC): Mouse liver Exposure time: 60s. |
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