GDF-8/Myostatin Rabbit mAb, Unconjugated, Monoclonal
Catalog Number:
ABB-A22725
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| Article Name: | GDF-8/Myostatin Rabbit mAb, Unconjugated, Monoclonal |
| Biozol Catalog Number: | ABB-A22725 |
| Supplier Catalog Number: | A22725 |
| Alternative Catalog Number: | ABB-A22725-100UL,ABB-A22725-20UL |
| Manufacturer: | ABclonal |
| Host: | Rabbit |
| Category: | Antikörper |
| Application: | ELISA, WB |
| Species Reactivity: | Human |
| Immunogen: | Recombinant protein (or fragment).This information is considered to be commercially sensitive. |
| Conjugation: | Unconjugated |
| Alternative Names: | GDF8, MSLHP, GDF-8/Myostatin |
| This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein negatively regulates skeletal muscle cell proliferation and differentiation. Mutations in this gene are associated with increased skeletal muscle mass in humans and other mammals. |
| Application Dilute: | WB,1:5000 - 1:20000|ELISA,Recommended starting concentration is 1 µg/mL. Please optimize the concentration based on your specific assay requirements. |
| Application Notes: | Cross-Reactivity: Human,Mouse,Rat. ResearchArea: Cancer,Signal Transduction,Cell Biology Developmental Biology,Growth factors,Immunology Inflammation,Cytokines. Shipping: Ice Bag |
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Western blot analysis of various lysates using GDF-8/Myostatin Rabbit mAb (A22725) at 1:10000 dilution incubated overnight at 4°C. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 45s. |
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