CYP7A1 Mouse mAb, Unconjugated, Monoclonal
Catalog Number:
ABB-A22897
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| Article Name: | CYP7A1 Mouse mAb, Unconjugated, Monoclonal |
| Biozol Catalog Number: | ABB-A22897 |
| Supplier Catalog Number: | A22897 |
| Alternative Catalog Number: | ABB-A22897-500UL,ABB-A22897-20UL,ABB-A22897-1000UL,ABB-A22897-100UL |
| Manufacturer: | ABclonal |
| Host: | Mouse |
| Category: | Antikörper |
| Application: | ELISA, WB |
| Species Reactivity: | Human |
| Immunogen: | Recombinant protein (or fragment).This information is considered to be commercially sensitive. |
| Conjugation: | Unconjugated |
| Alternative Names: | CP7A, CYP7, CYPVII, CYP7A1 |
| This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum membrane protein catalyzes the first reaction in the cholesterol catabolic pathway in the liver, which converts cholesterol to bile acids. This reaction is the rate limiting step and the major site of regulation of bile acid synthesis, which is the primary mechanism for the removal of cholesterol from the body. Polymorphisms in the promoter of this gene are associated with defects in bile acid synthesis. |
| Application Dilute: | WB,1:500 - 1:1000|ELISA,Recommended starting concentration is 1 µg/mL. Please optimize the concentration based on your specific assay requirements. |
| Application Notes: | Cross-Reactivity: Mouse,Rat. ResearchArea: Cancer,Signal Transduction,Endocrine Metabolism,Mitochondrial metabolism,Lipid Metabolism,Cholesterol Metabolism,Lipases,Cardiovascular,Lipids. Shipping: Ice Bag |
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Western blot analysis of various lysates using CYP7A1 Mouse mAb (A22897) at 1:1000 dilution incubated at room temperature for 1.5 hours. Secondary antibody: HRP-conjugated Goat anti-Mouse IgG (H+L) (AS003) at 1:10000 dilution. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 90 s. |
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