FLG Rabbit mAb, Unconjugated, Monoclonal

Catalog Number: ABB-A23193
Article Name: FLG Rabbit mAb, Unconjugated, Monoclonal
Biozol Catalog Number: ABB-A23193
Supplier Catalog Number: A23193
Alternative Catalog Number: ABB-A23193-100UL,ABB-A23193-20UL
Manufacturer: ABclonal
Host: Rabbit
Category: Antikörper
Application: ELISA, WB
Species Reactivity: Human
Immunogen: Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Conjugation: Unconjugated
Alternative Names: FLG1, ATOD2, FLG-1, FLG
The protein encoded by this gene is an intermediate filament-associated protein that aggregates keratin intermediate filaments in mammalian epidermis. It is initially synthesized as a polyprotein precursor, profilaggrin (consisting of multiple filaggrin units of 324 aa each), which is localized in keratohyalin granules, and is subsequently proteolytically processed into individual functional filaggrin molecules. Mutations in this gene are associated with ichthyosis vulgaris.
Clonality: Monoclonal
Molecular Weight: 435kDa
NCBI: 2312
UniProt: P20930
Purity: Affinity purification
Target: FLG
Application Dilute: WB,1:1000 - 1:5000|ELISA,Recommended starting concentration is 1 µg/mL. Please optimize the concentration based on your specific assay requirements.
Application Notes: Cross-Reactivity: Mouse,Rat. ResearchArea: Ichthyosis vulgaris, Intermediate filament-associated protein. Shipping: Ice Bag
Western blot analysis of various lysates, using FLG Rabbit mAb (A23193) at 1:2000 dilution.
Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.
Lysates/proteins: 25µg per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Detection: ECL Basic Kit (RM00020).
Exposure time: 1s.