Glutaredoxin 1 (GLRX) Rabbit mAb, Unconjugated, Monoclonal

Catalog Number: ABB-A23246
Article Name: Glutaredoxin 1 (GLRX) Rabbit mAb, Unconjugated, Monoclonal
Biozol Catalog Number: ABB-A23246
Supplier Catalog Number: A23246
Alternative Catalog Number: ABB-A23246-100UL,ABB-A23246-20UL
Manufacturer: ABclonal
Host: Rabbit
Category: Antikörper
Application: ELISA, WB
Species Reactivity: Human
Immunogen: Synthetic peptide. This information is considered to be commercially sensitive.
Conjugation: Unconjugated
Alternative Names: GRX, GRX1, Glutaredoxin 1 (GLRX)
This gene encodes a member of the glutaredoxin family. The encoded protein is a cytoplasmic enzyme catalyzing the reversible reduction of glutathione-protein mixed disulfides. This enzyme highly contributes to the antioxidant defense system. It is crucial for several signalling pathways by controlling the S-glutathionylation status of signalling mediators. It is involved in beta-amyloid toxicity and Alzheimers disease. Multiple alternatively spliced transcript variants encoding the same protein have been identified.
Clonality: Monoclonal
Molecular Weight: 12kDa
NCBI: 2745
UniProt: P35754
Purity: Affinity purification
Target: GLRX
Application Dilute: WB,1:500 - 1:1000|ELISA,Recommended starting concentration is 1 µg/mL. Please optimize the concentration based on your specific assay requirements.
Application Notes: Cross-Reactivity: Human,Mouse,Rat. ResearchArea: Cell Biology Developmental Biology,Endocrine Metabolism. Shipping: Ice Bag
Western blot analysis of various lysates, using Glutaredoxin 1(GLRX) Rabbit mAb (A23246) at 1:1000 dilution.
Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.
Lysates/proteins: 25µg per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Detection: ECL Basic Kit (RM00020).
Exposure time: 60s.