ULBP2 Rabbit mAb, Unconjugated, Monoclonal

Catalog Number: ABB-A23828
Article Name: ULBP2 Rabbit mAb, Unconjugated, Monoclonal
Biozol Catalog Number: ABB-A23828
Supplier Catalog Number: A23828
Alternative Catalog Number: ABB-A23828-100UL,ABB-A23828-20UL
Manufacturer: ABclonal
Host: Rabbit
Category: Antikörper
Application: ELISA, WB
Species Reactivity: Human
Immunogen: Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Conjugation: Unconjugated
Alternative Names: ULBP2, ALCAN-alpha, N2DL2, NKG2DL2, RAET1H, NKG2D ligand 2
This gene encodes a major histocompatibility complex (MHC) class I-related molecule that binds to the NKG2D receptor on natural killer (NK) cells to trigger release of multiple cytokines and chemokines that in turn contribute to the recruitment and activation of NK cells. The encoded protein undergoes further processing to generate the mature protein that is either anchored to membrane via a glycosylphosphatidylinositol moiety, or secreted. Many malignant cells secrete the encoded protein to evade immunosurveillance by NK cells. This gene is located in a cluster of multiple MHC class I-related genes on chromosome 6.
Clonality: Monoclonal
Molecular Weight: 27kDa
NCBI: 80328
UniProt: Q9BZM5
Purity: Affinity purification
Target: ULBP2
Application Dilute: WB,1:1000 - 1:5000|ELISA,Recommended starting concentration is 1 µg/mL. Please optimize the concentration based on your specific assay requirements.
Application Notes: Cross-Reactivity: Human. ResearchArea: Immunology & Inflammation,Toll-like Receptor Signaling Pathway,Cell Intrinsic Innate Immunity Signaling Pathway,TLR Signaling. Shipping: Ice Bag
Western blot analysis of various lysates, using ULBP2 Rabbit mAb (A23828) at 1:2000 dilution.
Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.
Lysates/proteins: 25µg per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Detection: ECL Basic Kit (RM00020).
Exposure time: 45s.