p16 INK4A Rabbit pAb, Unconjugated, Polyclonal
Catalog Number:
ABB-A23882
- Images (1)
| Article Name: | p16 INK4A Rabbit pAb, Unconjugated, Polyclonal |
| Biozol Catalog Number: | ABB-A23882 |
| Supplier Catalog Number: | A23882 |
| Alternative Catalog Number: | ABB-A23882-500UL,ABB-A23882-100UL,ABB-A23882-1000UL,ABB-A23882-20UL |
| Manufacturer: | ABclonal |
| Host: | Rabbit |
| Category: | Antikörper |
| Application: | ELISA, WB |
| Species Reactivity: | Mouse |
| Immunogen: | Recombinant protein (or fragment).This information is considered to be commercially sensitive. |
| Conjugation: | Unconjugated |
| Alternative Names: | Arf, p16, MTS1, Pctr1, p19ARF, p16INK4a, p19, ARF-INK4a, INK4a-ARF, Ink4a/Arf, p16(INK4a), p16 INK4A |
| Enables MDM2/MDM4 family protein binding activity, enzyme inhibitor activity, and protein N-terminus binding activity. Involved in several processes, including negative regulation of lymphocyte proliferation, positive regulation of apoptotic process, and regulation of transcription, DNA-templated. Acts upstream of or within several processes, including negative regulation of cellular protein metabolic process, negative regulation of mammary gland epithelial cell proliferation, and positive regulation of apoptotic process involved in mammary gland involution. Located in cytoplasm and granular component. Part of protein-containing complex. Is expressed in several structures, including bone marrow, central nervous system, dorsal root ganglion, eye, and testis. Human ortholog(s) of this gene implicated in several diseases, including breast cancer (multiple), carcinoma (multiple), hematologic cancer (multiple), melanoma (multiple), and nervous system cancer (multiple). Orthologous to human CDKN2A (cyclin dependent kinase inhibitor 2A). |
| Application Dilute: | WB,1:500 - 1:5000|ELISA,Recommended starting concentration is 1 µg/mL. Please optimize the concentration based on your specific assay requirements. |
| Application Notes: | Cross-Reactivity: Human,Mouse,Rat. Shipping: Ice Bag |
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Western blot analysis of various lysates, using p16 INK4A Rabbit pAb (A23882) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution. Lysates/proteins: 25µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 45s. |
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