Na /K -ATPase Rabbit pAb, Unconjugated, Polyclonal
Catalog Number:
ABB-A24883
- Images (1)
| Article Name: | Na /K -ATPase Rabbit pAb, Unconjugated, Polyclonal |
| Biozol Catalog Number: | ABB-A24883 |
| Supplier Catalog Number: | A24883 |
| Alternative Catalog Number: | ABB-A24883-100UL,ABB-A24883-20UL,ABB-A24883-500UL,ABB-A24883-1000UL |
| Manufacturer: | ABclonal |
| Host: | Rabbit |
| Category: | Antikörper |
| Application: | ELISA, WB |
| Species Reactivity: | Human |
| Immunogen: | Recombinant protein (or fragment).This information is considered to be commercially sensitive. |
| Conjugation: | Unconjugated |
| Alternative Names: | ATP1A1, ATPase Na+/K+ transporting subunit alpha 1, Na /K -ATPase |
| The protein encoded by this gene belongs to the family of P-type cation transport ATPases, and to the subfamily of Na+/K+ -ATPases. Na+/K+ -ATPase is an integral membrane protein responsible for establishing and maintaining the electrochemical gradients of Na and K ions across the plasma membrane. These gradients are essential for osmoregulation, for sodium-coupled transport of a variety of organic and inorganic molecules, and for electrical excitability of nerve and muscle. This enzyme is composed of two subunits, a large catalytic subunit (alpha) and a smaller glycoprotein subunit (beta). The catalytic subunit of Na+/K+ -ATPase is encoded by multiple genes. This gene encodes an alpha 1 subunit. Multiple transcript variants encoding different isoforms have been found for this gene. |
| Clonality: | Polyclonal |
| Molecular Weight: | 74kDa/109kDa/112kDa/113kDa |
| NCBI: | 476 |
| UniProt: | P05023 |
| Purity: | Affinity purification |
| Sequence: | MTVAHMWFDNQIHEADTTENQSGVSFDKTSATWLALSRIAGLCNRAVFQANQENLPILKRAVAGDASESALLKCIELCCGSVKEMRERYAKIVEIPFNSTNKYQLSIHKNPNTSEPQHLLVMKGAPERILDRCSSILLHGKEQPLDEELKDAFQNAYLELGGLGERVLGFCHLFLPDEQFPEGFQFDTDDVNFPIDNLCFVGLISMIDPP |
| Target: | Na /K -ATPase |
| Antibody Type: | Primary Antibody |
| Application Dilute: | WB,1:500 - 1:1000|ELISA,Recommended starting concentration is 1 µg/mL. Please optimize the concentration based on your specific assay requirements. |
| Application Notes: | Cross-Reactivity: Rat. ResearchArea: Signal Transduction,Endocrine & Metabolism. Shipping: Ice Bag |
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Western blot analysis of lysates from C6 cells usingNa /K -ATPase Rabbit pAb (A24883) at1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution. Lysates/proteins: 25µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 45s. |
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