Peptide sequence around aa. 395~399 (D-D-Y-A-E) derived from Human FAK.
Alternative Names:
FADK|| PTK2|| FAK1|| FRNK|| PTK2
Important regulator of cell cycle progression. Involved in G1 arrest. Potent inhibitor of cyclin E- and cyclin A-CDK2 complexes. Positive regulator of cyclin D-dependent kinases such as CDK4. Regulated by phosphorylation and degradation events. von Sengbusch A, et al. (2005) Am J Pathol , 166(2): 585-596 Fornaro M, et al. (2000) Mol Biol Cell , 11(7): 2235-2249 Zhang X, et al. (1999) Proc Natl Acad Sci U S A, 96(16): 9021-9026.
