Peptide sequence around aa.218~222 (P-E-T-P-P) derived from Human Smad2.
Alternative Names:
JV18-1|| MADH2|| MADR2|| Mad-related protein 2|| Mothers against DPP homolog 2
Transcriptional modulator activated by TGF-beta and activin type 1 receptor kinase. SMAD2 is a receptor-regulated SMAD (R-SMAD). May act as a tumor suppressor in colorectal carcinoma.