Peptide sequence around aa.703~707 (T-D-Y -Y-R) derived from Human TrkB.
Alternative Names:
TRKB|| trk-B|| GP145-TrkB
Receptor for brain-derived neurotrophic factor (BDNF), neurotrophin-3 and neurotrophin-4/5 but not nerve growth factor (NGF). Involved in the development and/or maintenance of the nervous system. This is a tyrosine-protein kinase receptor. Known substrates for the TRK receptors are SHC1, PI-3 kinase, and PLC-gamma-1. Woronowicz A, et al. Glycobiology. 2007 Jan,17(1):10-24. Mojsilovic-Petrovic J, et al. J Neurosci. 2006 Sep 6,26(36):9250-63. Lewis MA, et al. Mol Pharmacol. 2006 Apr,69(4):1396-404. Cai D, et al. Physiol Genomics. 2006 Feb 14,24(3):191-7.
