Peptide sequence around aa. 353~357 (S-G-I-S-S) derived from Human CK2?.
Alternative Names:
CKII|| CK2A1|| CSNK2A1
Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. The a and a chains contain the catalytic site. Participates in Wnt signaling. CK2 phosphorylates Ser-392 of p53/TP53 following UV irradiation. Keller D.M., Zeng X., et al., Mol. Cell 7:283-292(2001) Keller D.M., Lu H. et al., J. Biol. Chem. 277:50206-50213(2002) Trembley J.H., Tatsumi S., et al., Mol. Cell. Biol. 25:1446-1457(2005) Niefind K., Guerra B., et al., Acta Crystallogr. D 56:1680-1684(2000)
