Peptide sequence around aa.461-465(I-S-S-V-S) derived from Human Smad1. This sequence has the same homology in Smad5 and Smad8.
Alternative Names:
Mad-related protein 1||SMAD 1||hSMAD1||Transforming growth factor-beta-signaling protein 1
Transcriptional modulator activated by BMP (bone morphogenetic proteins) type 1 receptor kinase. SMAD1 is a receptor-regulated SMAD (R-SMAD).SMAD5 is a receptor-regulated SMAD (R-SMAD). SMAD9 is a receptor-regulated SMAD (R-SMAD). Has been shown to be activated by activin type I receptor-like kinases (ALK-2, ALK-3, ALK-6) which stimulate heteromerization between SMAD9 and SMAD4. May play a role in osteoblast differentiation and maturation.
Clonality:
Polyclonal
Form:
Purified
Target:
Smad1/Smad5/Smad8
Application Dilute:
Predicted MW: 60kd, Western blotting: 1: 500~1: 1000
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