This MAb reacts with a protein of ~13kDa, identified as alpha sub-unit of HCG. HCG is a glycoprotein, which is secreted in large quantities by normal trophoblasts. It is present only in trace amounts in non-pregnant urine and sera but rises sharply during pregnancy. HCG is composed of two non-identical, non-covalently linked polypeptide chains designated as the alpha and beta subunits. The alpha subunit is identical to that of thyroid stimulating hormone (TSH), follicle stimulating hormone (FSH), and luteinizing hormone (LH).
HCG-alpha (Pregnancy & Choriocarcinoma Marker)
Application Dilute:
Immunohistochemistry (Formalin-fixed) (1-2ug/ml for 30 minutes at RT)(No special pre-treatment is required for staining of formalin-fixed tissues. Note that HIER is NOT recommended for this antibody.)
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