Monoclonal Antibody to Chromogranin A / CHGA (Neuroendocrine Marker)(Clone : CHGA/777), Clone: [CHGA/777], Mouse
Biozol Catalog Number:
ABI-36-1055
Supplier Catalog Number:
36-1055
Alternative Catalog Number:
ABI-36-1055-100UG
Manufacturer:
Abeomics
Host:
Mouse
Category:
Antikörper
Application:
IHC, WB
Species Reactivity:
Human
Immunogen:
Recombinant full-length human CHGA protein
Alternative Names:
CHGA
Chromogranin A is present in neuroendocrine cells throughout the body, including the neuroendocrine cells of the large and small intestine, adrenal medulla and pancreatic islets. It is an excellent marker for carcinoid tumors, pheochromocytomas, paragangliomas, and other neuroendocrine tumors. Co-expression of chromogranin A and neuron specific enolase (NSE) is common in neuroendocrine neoplasms. Reportedly, co-expression of certain keratins and chromogranin indicates neuroendocrine lineage. The presence of strong anti-chromogranin staining and absence of anti-keratin staining should raise the possibility of paraganglioma. The co-expression of chromogranin and NSE is typical of neuroendocrine neoplasms. Most pituitary adenomas and prolactinomas readily express chromogranin.
Western Blot (1-2ug/ml), Immunohistochemistry (Formalin-fixed) (1-2ug/ml for 30 minutes at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95&degC followed by cooling at RT for
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