Monoclonal Antibody to Hepatocyte Specific Antigen (Hepatocellular Marker)(Clone : SPM582), Clone: [SPM582], Mouse
Biozol Catalog Number:
ABI-36-11053
Supplier Catalog Number:
36-11053
Alternative Catalog Number:
ABI-36-11053-100UG
Manufacturer:
Abeomics
Host:
Mouse
Category:
Antikörper
Application:
IF, IHC
Species Reactivity:
Human
Immunogen:
Extract of a formalin-fixed, rejected-allograft of a human liver
Hepatocyte Specific Antigen, also called Hepatocyte Paraffin 1 or Hep Par 1, localizes to the mitochondria of hepatocytes. It is a sensitive marker for distinguishing hepatocellular carcinomas (HCC) from other metastatic carcinomas as well as cholangio-carcinomas. HCCs occur primarily in the stomach, but they are also found in many other organs. The Hepatocyte Specific Antigen may also be a useful marker for intestinal metaplasia. Reportedly, strong expression of the Hepatocyte Specific Antigen correlates with smaller tumor size and longer patient survival. Occasionally, Hepatocyte Specific Antigen is also found in gastric carcinomas as well as in a few other non-hepatic tumors.
Clonality:
Monoclonal
Clone Designation:
[SPM582]
Purity:
Affinity Chromatography
Form:
Purified
Target:
Hepatocyte Specific Antigen (Hepatocellular Marker)
Application Dilute:
Immunofluorescence (1-2ug/ml), Immunohistochemistry (Formalin-fixed) (1-2ug/ml for 30 minutes at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 1mM EDTA, pH 7.5-8.5, for 45 min at 95&degC followed by cooling at RT for 20 mi
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