Monoclonal Antibody to Calgranulin B (Macrophage Marker)(Clone : CAGB/426), Clone: [CAGB/426], Mouse
Biozol Catalog Number:
ABI-36-1668
Supplier Catalog Number:
36-1668
Alternative Catalog Number:
ABI-36-1668-100UG
Manufacturer:
Abeomics
Host:
Mouse
Category:
Antikörper
Application:
IHC
Species Reactivity:
Human
Immunogen:
Recombinant human CAGB protein
Alternative Names:
S100A9||CAGB||CFAG||MRP14
Recognizes a 12-14kDa doublet of Calgranulin A/B (also known as S100A8/A9 or MRP-8/14), expressed by granulocytes, monocytes and by tissue macrophages. The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. Altered expression of this protein is associated with the disease cystic fibrosis. This MAb reacts with neutrophils, monocytes, macrophages, and squamous mucosal epithelia and has been shown as an important marker for identifying macrophages in tissue sections.
Immunohistochemistry (Formalin-fixed. Not suitable for frozen tissues.) (1-2ug/ml for 30 minutes at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95&degC followed by cooling a
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