Monoclonal Antibody to GRP94 / HSP90B1 (Endoplasmic Reticulum Marker)(Clone : HSP90B1/1192), Clone: [HSP90B1/1192], Rat
Biozol Catalog Number:
ABI-36-1766
Supplier Catalog Number:
36-1766
Alternative Catalog Number:
ABI-36-1766-100UG
Manufacturer:
Abeomics
Host:
Rat
Category:
Antikörper
Application:
IHC
Species Reactivity:
Human
Immunogen:
Recombinant full-length human HSP90B1 protein
Alternative Names:
HSP90B1||GRP94||TRA1
Recognizes a protein of 94kDa, which is identified as the glucose-regulated protein 94 (grp94) and also tumor rejection antigen (gp96). Grp94 shows a high degree of sequence homology with the heat shock protein 90 (hsp90). This MAb is highly specific to grp94 and shows minimal cross-reaction with other members of the HSP90 family. Grp s are a class of proteins unresponsive to heat shock and are induced by glucose deprivation. Grp94 has been briefly studied as a prognostic factor in breast cancer.
Immunohistochemistry (Formalin-fixed) (1-2ug/ml for 30 minutes at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95&degC followed by cooling at RT for 20 minutes),
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