Polyclonal Antibody to Uroplakin 3A (Bladder Carcinoma Marker), Rat
Biozol Catalog Number:
ABI-36-1793
Supplier Catalog Number:
36-1793
Alternative Catalog Number:
ABI-36-1793-100UG
Manufacturer:
Abeomics
Host:
Rat
Category:
Antikörper
Application:
WB
Species Reactivity:
Human
Immunogen:
A synthetic peptide, aa260-279 (GASESSYTSVNRGPPLDRAE) of human UPK3A
Alternative Names:
UPK3A||UPK3
Uroplakin-3A (UPK3A) is a component of the asymmetric unit membrane (AUM). It is a highly specialized bio-membrane made by terminally differentiated urothelial cells. The protein may play an important role in AUM-cytoskeleton interaction in terminally differentiated urothelial cells. UPK3A also contributes to the formation of urothelial glycocalyx, which may play an important role in preventing bacterial adherence through FimH bacterial protein binding leading to bladder infection. UPK3A has been shown as a helpful marker for the detection of bladder cancer.
