Monoclonal Antibody to von Willebrand Factor / Factor VIII Related-Ag (Endothelial Marker)(3E2D10 + VWF635), Clone: [3E2D10 + VWF635], Mouse
Biozol Catalog Number:
ABI-36-1806
Supplier Catalog Number:
36-1806
Alternative Catalog Number:
ABI-36-1806-100UG
Manufacturer:
Abeomics
Host:
Mouse
Category:
Antikörper
Application:
FACS, IF, IHC, IP, WB
Species Reactivity:
Human
Immunogen:
Recombinant human vWF fragment
Alternative Names:
VWF||F8VWF
von Willebrand Factor (vWF) is a multimeric glycoprotein that is found in endothelial cells, plasma and platelets. It acts as a carrier protein for Factor VIII and promotes platelet adhesion and aggregation. vWF undergoes a variety of posttranslational modifications that influence the affinity and availability for Factor VIII, including cleavage of the propeptide and formation of N-terminal disulfide bonds. This antibody helps to establish the endothelial nature of some lesions of disputed histogenesis, e.g. Kaposis sarcoma and cardiac myxoma. It is widely used for differentiating vascular lesions from those of other tissue differentiation within a panel of other vascular markers although not all tumors of endothelial differentiation contain this antigen.
von Willebrand Factor / Factor VIII Related-Ag (Endothelial Marker)
Application Dilute:
Immunoprecipitation (1-2 g/500ug protein lysate), Flow Cytometry (1-2ug/million cells), ,Immunofluorescence (1-2ug/ml), Western Blot (1-2ug/ml), ,Immunohistochemistry (Formalin-fixed) (1-2ug/ml for 30 minutes at RT),(Staining of formalin-fixed tissues req
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