Anti-FABP5 (Marker of Metastatic Potential in Colorectal Cancer) Monoclonal Antibody(Clone: FABP5/3750), Clone: [FABP5/3750], Mouse
Biozol Catalog Number:
ABI-36-2275-20
Supplier Catalog Number:
36-2275-20
Alternative Catalog Number:
ABI-36-2275-20-20UG
Manufacturer:
Abeomics
Host:
Mouse
Category:
Antikörper
Application:
IHC, WB
Species Reactivity:
Human
Immunogen:
Recombinant full-length human FABP5 protein
Alternative Names:
FABP5, E-FABP, EFABP, PA-FABP, PAFABP
This gene encodes the fatty acid binding protein found in epidermal cells, and was first identified as being upregulated in psoriasis tissue. Fatty acid binding proteins are a family of small, highly conserved, cytoplasmic proteins that bind long-chain fatty acids and other hydrophobic ligands. FABPs may play roles in fatty acid uptake, transport, and metabolism. Polymorphisms in this gene are associated with type 2 diabetes. The human genome contains many pseudogenes similar to this locus. FABP5 is also associated with poor survival in triple-negative breast cancer. Additionally, FABP5 gene is upregulated in colorectal cancer cells compared to normal colon cells in a manner that correlates with disease stage and that FABP5 significantly promotes colorectal cancer cell growth and metastatic potential.
Western Blotting (1-2ug/ml), ,Immunohistology (Formalin-fixed) (1-2ug/ml for 30 min at RT),(Staining of formalin-fixed tissues requires boiling tissue sections in 10mM Citrate Buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes),
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