Anti-PD-L1 / PDCD1LG1 / CD274 / B7-H1 (Cancer Immunotherapy Target) Monoclonal Antibody(Clone: PDL1/2746), Clone: [PDL1/2746], Mouse

Catalog Number: ABI-36-2431-20
Article Name: Anti-PD-L1 / PDCD1LG1 / CD274 / B7-H1 (Cancer Immunotherapy Target) Monoclonal Antibody(Clone: PDL1/2746), Clone: [PDL1/2746], Mouse
Biozol Catalog Number: ABI-36-2431-20
Supplier Catalog Number: 36-2431-20
Alternative Catalog Number: ABI-36-2431-20-20UG
Manufacturer: Abeomics
Host: Mouse
Category: Antikörper
Application: ELISA, FACS, IF, IHC, WB
Species Reactivity: Human
Immunogen: Recombinant fragment (around aa 39-191) of human CD274 (PD-L1) protein (exact sequence is proprietary)
Alternative Names: B7 homolog 1, B7-H1, CD274, PD-L1, PDCD1 ligand 1, PDCD1L1, PDCD1LG1, Programmed cell death 1 ligand 1
PD-L1 is a checkpoint regulator in immune cells, it is expressed on immune or non-hematopoietic cells. Expression of the protein is seen during pregnancy where it has a role in suppressing the immune system. PD-L1 induces an inhibitory signal in activated T-cells and promotes T-cell apoptosis. It is overexpressed in a number of different cancers where it is believed to play a significant role in the cancer s ability to evade the immune system.
Clonality: Monoclonal
Clone Designation: [PDL1/2746]
NCBI: 29126
UniProt: Q9NZQ7
Application Dilute: ELISA (For coating, order antibody without BSA), Western Blot (1-2ug/ml),,Flow Cytometry (1-2ug/million cells), Immunofluorescence (1-2ug/ml),,Immunohistochemistry (Formalin-fixed) (1-2ug/ml for 30 minutes at RT),(Staining of formalin-fixed tissues requir