Anti-Tenascin C (Stromal Marker for Epithelial Malignancy) Monoclonal Antibody(Clone: TNC/3635), Clone: [TNC/3635], Mouse

Catalog Number: ABI-36-2512
Article Name: Anti-Tenascin C (Stromal Marker for Epithelial Malignancy) Monoclonal Antibody(Clone: TNC/3635), Clone: [TNC/3635], Mouse
Biozol Catalog Number: ABI-36-2512
Supplier Catalog Number: 36-2512
Alternative Catalog Number: ABI-36-2512-100UG
Manufacturer: Abeomics
Host: Mouse
Category: Antikörper
Application: IHC
Species Reactivity: Human
Immunogen: Recombinant human full-length TNC protein
Alternative Names: Cytotactin, Glioma-associated-extracellular matrix antigen, GMEM, GP 150-225, Hexabrachion (HXB), JI, Myotendinous antigen, Neuronectin, TNC
In Western blotting, it reacts with two bands of ~MW of 210kDa and 300kDa, identified as two isoforms of Tenascin C. Specificity of this MAb is validated by sequential immunoprecipitation with a PAb against Tenascin C. Tenascin C is a multifunctional, disulfide-linkedhexameric extracellular matrix glycoprotein expressed in association with mesenchymal epithelial interactions during development and in the neo-vasculature and stroma of undifferentiated tumors. In adults, it is restricted to certain epithelial-stromal interfaces and increases markedly in hyper-proliferative diseases and in stroma of many neoplasms, including gliomas, breast, squamous and lung carcinomas.
Clonality: Monoclonal
Clone Designation: [TNC/3635]
NCBI: 3371
UniProt: P24821
Application Dilute: Immunohistochemistry (Formalin-fixed) (2-4ug/ml for 30 minutes at RT),(Staining of formalin-fixed tissues requires boiling tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 10-20 min followed by cooling at RT for 20 minutes) ,