Anti-IgG (Immunoglobulin Gamma Heavy Chain) (B-Cell Marker) Polyclonal Antibody, Rabbit

Catalog Number: ABI-36-2546
Article Name: Anti-IgG (Immunoglobulin Gamma Heavy Chain) (B-Cell Marker) Polyclonal Antibody, Rabbit
Biozol Catalog Number: ABI-36-2546
Supplier Catalog Number: 36-2546
Alternative Catalog Number: ABI-36-2546-100UG
Manufacturer: Abeomics
Host: Rabbit
Category: Antikörper
Application: IHC
Species Reactivity: Human
Immunogen: Purified human Ig Gamma Chain
Alternative Names: G1m Marker, G2m Marker, G3m Marker, G4m Marker, HDC, Heavy Chain Disease Protein, Human Immunglobulin G, Ig gamma1/2/3/4 Chain C Region, IGHG1, IGHG2, IGHG3, IGHG4, Immunoglobulin Heavy Constant 1/2/3/4
Recognizes a protein of 75kDa, identified as gamma heavy chain of human immunoglobulins. It does not cross-react with alpha (IgA), mu (IgM), epsilon (IgE), or delta (IgD), heavy chains, T-cells, monocytes, granulocytes, or erythrocytes. This antibody is useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkins lymphomas. The most common feature of these malignancies is the restricted expression of a single heavy chain class. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is clonal and therefore malignant.
Clonality: Polyclonal
NCBI: 3500
UniProt: P01857
Application Dilute: Immunohistochemistry (Formalin-fixed) (1-2ug/ml for 30 minutes at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95&degC followed by cooling at RT for 20 minutes),