It recognizes a protein of 80-87kDa, identified as gamma-catenin. The catenins (-T-catenin, is located on chromosome 10, and mutations in this gene show a strong correlation to late-onset Alzheimers disease (LOAD) as well as to dilated cardiomyopathy.
Flow Cytometry (1-2ug/million cells), Immunofluorescence (1-2ug/ml), Western Blot (1-2ug/ml), Immunohistochemistry (Formalin-fixed) (1-2ug/ml for 30 min at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA,
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