Recombinant fragment of human BARX1 protein (around aa 155-254) (exact sequence is proprietary)
Alternative Names:
BarH like homeobox 1, BarX 1, BARX homeobox 1, Homeobox protein BarH like 1
BarX1 is a member of the Bar subclass of homeobox transcription factors. Studies of the Mouse and chick homolog sµggest the encoded protein may play a role in developing teeth and craniofacial mesenchyme of neural crest origin. The protein may also be associated with differentiation of stomach epithelia. Down-regulation of Barx1 promotes HCC migration, invasion and metastasis, whereas up-regulation of Barx1 inhibits HCC migration, invasion and metastasis. The loss of Barx1 expression represents a prognostic biomarker in human HCC.
Immunohistochemistry (Formalin-fixed) (1-2ug/ml for 30 min at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95&degC followed by cooling at RT for 20 minutes),
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