Polyclonal Antibody to CD134/OX40/TNFRSF4, Rabbit, Monoclonal
Biozol Catalog Number:
ABI-39-2171
Supplier Catalog Number:
39-2171
Alternative Catalog Number:
ABI-39-2171-100UG
Manufacturer:
Abeomics
Host:
Rabbit
Category:
Antikörper
Application:
FACS, ICC, IHC, WB
Species Reactivity:
Human
Immunogen:
A synthetic peptide corresponding to a sequence at the C-terminus of human CD134/OX40 (232-254aa AILLALYLLRRDQRLPPDAHKPP), different from the related mouse sequence by ten amino acids.
Alternative Names:
Tumor necrosis factor receptor superfamily member 4,ACT35 antigen,OX40L receptor,TAX
Tumor necrosis factor receptor superfamily, member 4, also known as ACT35 or CD134, is a cell surface glycoprotein that was discovered through the production of a monoclonal antibody raised against the HUT-102 cell line. It belongs to the tumor necrosis factor receptor superfamily. CD134 was mapped to 1p36 by fluorescence in situ hybridization. CD134 is the primary receptor for feline immunodeficiency virus. And CD134 expression can promote viral binding and renders cells permissive for viral entry, productive infection, and syncytium formation. Stimulating the receptor can improve the response to a powerful virus vector and may be useful in vaccine development.
