Human C5AR1 Full Length Protein (VLP), Unconjugated
Biozol Catalog Number:
ABS-C51-H52P4-20UG
Supplier Catalog Number:
C51-H52P4-20ug
Alternative Catalog Number:
ABS-C51-H52P4-20UG
Manufacturer:
AcroBiosystems
Host:
Human
Category:
Proteine/Peptide
Species Reactivity:
Human
Conjugation:
Unconjugated
Complement Component 5a Receptor 1 (C5aR1), also known as CD88, is a highaffinity G proteincoupled receptor (GPCR) essential for mediating potent inflammatory responses. In the tumor microenvironment, C5aR1 activation on myeloidderived suppressor cells (MDSCs) facilitates immune evasion and metastasis. Crucially, C5aR1 interacts with glycosaminoglycans (GAGs), such as heparin, which act as coreceptors or modulators. These C5aR1GAG interactions influence ligand recruitment and receptor signaling, making this axis a prime target for developing therapeutic antibodies and smallmolecule inhibitors in oncology and autoimmune disorders. - Proteine/Peptide
