Mouse CCR8 Full Length Protein (VLP), Unconjugated, Human
Biozol Catalog Number:
ABS-CC8-M52P3-500UG
Supplier Catalog Number:
CC8-M52P3-500ug
Alternative Catalog Number:
ABS-CC8-M52P3-500UG
Manufacturer:
AcroBiosystems
Host:
Human
Category:
Proteine/Peptide
Species Reactivity:
Mouse
Conjugation:
Unconjugated
CCR8 is a G proteincoupled receptor predominantly expressed on tumorinfiltrating regulatory T cells (Tregs), where it drives immunosuppression within the tumor microenvironment. Its highly restricted expression pattern makes it a precision target for cancer immunotherapy. By selectively depleting these CCR8+ Tregs, antibody drugs can reinvigorate antitumor immunity without the systemic toxicity of broader immunotherapies - Proteine/Peptide
