Mouse CD5 Protein, His Tag (MALS verified), Unconjugated, Human
Biozol Catalog Number:
ABS-CD5-M52H4-100UG
Supplier Catalog Number:
CD5-M52H4-100ug
Alternative Catalog Number:
ABS-CD5-M52H4-100UG
Manufacturer:
AcroBiosystems
Host:
Human
Category:
Proteine/Peptide
Species Reactivity:
Mouse
Conjugation:
Unconjugated
Tcell surface glycoprotein CD5 is also known as Lymphocyte antigen T1/Leu1 and LEU1,which is phosphorylated on tyrosine residues by LYN,so CD5 can create binding sites for PTPN6/SHP1.CD5 may act as a receptor in regulating Tcell proliferation. CD5 is expressed at various developmental and activation stages on human B cells.CD5 is a well established negative regulator of TCR and BCR signalling.CD5positive cells may also prevent the emergence of autoimmunity by provision of cytokines such as IL10. Development,selection and function of different B and Tcell subsets or their preferential survival may be directly or indirectly dependent on different glycan structures associated with CD5 or CD5like molecules. - Proteine/Peptide
