Biotinylated Human CNTF R alpha Protein, His,Avitag(TM)
Biozol Catalog Number:
ABS-CNR-H82Q3-200UG
Supplier Catalog Number:
CNR-H82Q3-200ug
Alternative Catalog Number:
ABS-CNR-H82Q3-200UG
Manufacturer:
AcroBiosystems
Host:
Human
Category:
Proteine/Peptide
Species Reactivity:
Human
Conjugation:
Biotin
CNTF receptor alpha (CNTFR) is a specialized protein primarily expressed in the nervous system and skeletal muscle. Unlike many receptors, it lacks a transmembrane domain and anchors to the cell surface via a GPI linkage. It functions as a crucial signaling component that binds Ciliary Neurotrophic Factor, subsequently recruiting gp130 and LIFR to initiate the JAK/STAT pathway. This process is vital for promoting neuronal survival, guiding motor neuron development, and regulating muscle regeneration. - Proteine/Peptide
