Human gp130 & OSMR Heterodimer Protein, His Tag (MALS verified), Unconjugated
Biozol Catalog Number:
ABS-GPR-H52H3-100UG
Supplier Catalog Number:
GPR-H52H3-100ug
Alternative Catalog Number:
ABS-GPR-H52H3-100UG
Manufacturer:
AcroBiosystems
Host:
Human
Category:
Proteine/Peptide
Species Reactivity:
Human
Conjugation:
Unconjugated
OSM signaling on responsive cells is mediated by binding to two distinct signaling receptor complexes identified as type I and type II OSM receptors. Type II OSM receptor (gp130/OSMRbeta) is a heterodimer composed of gp130 and OSM receptor beta subunit. The type II receptor has OSM specificity. This receptor triggers the activation of associated Janus kinases (JAKs), leading primarily to the phosphorylation and activation of the Signal Transducer and Activator of Transcription 3 (STAT3) pathway. - Proteine/Peptide
