Tyrosinase-Related Protein-1 (TYRP-1) (Melanoma Marker) Antibody - With BSA and Azide, Clone: [SPM456], Mouse, Monoclonal
Catalog Number:
ABT-AH10795-U0020
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| Article Name: | Tyrosinase-Related Protein-1 (TYRP-1) (Melanoma Marker) Antibody - With BSA and Azide, Clone: [SPM456], Mouse, Monoclonal |
| Biozol Catalog Number: | ABT-AH10795-U0020 |
| Supplier Catalog Number: | AH10795-U0020 |
| Alternative Catalog Number: | ABT-AH10795-U0020-20UG |
| Manufacturer: | Abcepta |
| Host: | Mouse |
| Category: | Antikörper |
| Application: | FC, IF, IHC-Fr |
| Species Reactivity: | Human, Mouse |
| Alternative Names: | 5,6-dihydroxyindole-2-carboxylic acid oxidase, DHICA oxidase, 1.14.18.-, Catalase B, Glycoprotein 75, Melanoma antigen gp75, Tyrosinase-related protein 1, TRP, TRP-1, TRP1, TYRP1, CAS2, TYRP, TYRRP |
| It reacts with a 75kDa melanocyte-specific gene product, identified as Tyrosinase-related protein-1 (TRP-1). It is involved in melanin synthesis. TRP1 is present on the melanosomal membranes of melanoma, normal melanocytes and nevi.ĀRecent evidence suggests that TRP-1 is involved in maintaining stability of tyrosinase protein and modulating its catalytic activity. TRP-1 is also involved in maintenance of melanosome ultrastructure and affects melanocyte proliferation and cell death. |
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