CD8A (Anti-Mouse) (Cytotoxic / Suppressor T-Cell Marker) Antibody - With BSA and Azide, Clone: [IBL-3/25], Rat, Monoclonal
Catalog Number:
ABT-AH10904-U0100
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| Article Name: | CD8A (Anti-Mouse) (Cytotoxic / Suppressor T-Cell Marker) Antibody - With BSA and Azide, Clone: [IBL-3/25], Rat, Monoclonal |
| Biozol Catalog Number: | ABT-AH10904-U0100 |
| Supplier Catalog Number: | AH10904-U0100 |
| Alternative Catalog Number: | ABT-AH10904-U0100-100UG |
| Manufacturer: | Abcepta |
| Host: | Rat |
| Category: | Antikörper |
| Application: | FC, IF |
| Species Reactivity: | Mouse |
| Alternative Names: | T-cell surface glycoprotein CD8 alpha chain, T-cell surface glycoprotein Lyt-2, CD8a, Cd8a, Lyt-2, Lyt2 |
| Recognizes a protein of 32kDa, identified as CD8a (also known as CD8 chain, T cell co-receptor). CD8 molecule consists of two chains, termed and chain, which are expressed as a disulphide-linked heterodimer or as an homodimer. CD8 is expressed on T cell subset (cytotoxic/suppressor T cells), thymocytes and NK cells. The majority of CD8+ T-cells expresses CD8 as heterodimer. Some subpopulation of CD8+ T cells as well as NK cells may express homodimer. CD8 functions as a co-receptor in concert with TCR for binding the MHC class I/peptide complex. The HIV-2 envelope glycoprotein binds CD8 chain (but not chain). The cytoplasmic domain of CD8 associates with p56lck tyrosine kinase. |
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