CD16 / Fc-gamma Receptor III Antibody - With BSA and Azide, Clone: [HuNK2], Mouse, Monoclonal
Catalog Number:
ABT-AH11208-U0020
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| Article Name: | CD16 / Fc-gamma Receptor III Antibody - With BSA and Azide, Clone: [HuNK2], Mouse, Monoclonal |
| Biozol Catalog Number: | ABT-AH11208-U0020 |
| Supplier Catalog Number: | AH11208-U0020 |
| Alternative Catalog Number: | ABT-AH11208-U0020-20UG |
| Manufacturer: | Abcepta |
| Host: | Mouse |
| Category: | Antikörper |
| Application: | FC, IF |
| Species Reactivity: | Human |
| Alternative Names: | Low affinity immunoglobulin gamma Fc region receptor III-A, CD16a antigen, Fc-gamma RIII-alpha, Fc-gamma RIII, Fc-gamma RIIIa, FcRIII, FcRIIIa, FcR-10, IgG Fc receptor III-2, CD16a, FCGR3A, CD16A, FCG3, FCGR3, IGFR3 |
| Recognizes a protein of 50-65kDa, identified as CD16 (Workshop IV, Code N39 ) (also known low affinity Fc receptor III for IgG (FcRIII) or Leu 11). CD16 exists as a polypepetide-anchored from (FCRIIIA or CD16A) on human natural killer (NK) cells and monocytes/ macrophages and as a glycosylphosphatidylinositol (GPI)-anchored form (FcRIIIB or CD16B) on neutrophils. CD16B is polymorphic and the two alleles are termed NA1 and NA2.3 CD16 plays a role in signal transduction, NK cell activation and antibody-dependent cellular cytotoxicity. This MAb has been showed to inhibit the binding of immune complex to NK cells, inhibit cytotoxicity of NK cells, and induce calcium fluxes in NK cells and neutrophils. |
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