CD18 / Integrin beta-2 (ITGB2) Antibody - With BSA and Azide, Clone: [68-5A5], Mouse, Monoclonal
Catalog Number:
ABT-AH11611-U0020
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| Article Name: | CD18 / Integrin beta-2 (ITGB2) Antibody - With BSA and Azide, Clone: [68-5A5], Mouse, Monoclonal |
| Biozol Catalog Number: | ABT-AH11611-U0020 |
| Supplier Catalog Number: | AH11611-U0020 |
| Alternative Catalog Number: | ABT-AH11611-U0020-20UG |
| Manufacturer: | Abcepta |
| Host: | Mouse |
| Category: | Antikörper |
| Application: | FC, IF |
| Species Reactivity: | Human |
| Alternative Names: | Integrin beta-2, Cell surface adhesion glycoproteins LFA-1/CR3/p150,95 subunit beta, Complement receptor C3 subunit beta, CD18, ITGB2, CD18, MFI7 |
| It recognizes a transmembrane glycoprotein of 95kDa, identified as CD18 or integrin -2 (Workshop III). It complexes non-covalently with either L, M, or X integrin (CD11a, b, or c) to form the heterodimers, LFA-1, Mac-1, and p150,95, respectively. LFA-1 is the receptor for three members of the Ig supergene family of proteins, ICAM-1 (CD54), ICAM-2 (CD102), and Mac-1 and p150,95 bind to ICAM-1, fibrinogen, and iC3b. ICAM-3 (CD50). CD18/CD11 heterodimeric molecules are involved with cell/cell and cell/extracellular adhesion in immune and inflammatory responses. This MAb blocks these cellular interactions. |
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