MUC5AC (Mucin 5AC / Gastric Mucin) Antibody - With BSA and Azide, Clone: [9-13M1], Mouse, Monoclonal
Catalog Number:
ABT-AH11906-U0020
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| Article Name: | MUC5AC (Mucin 5AC / Gastric Mucin) Antibody - With BSA and Azide, Clone: [9-13M1], Mouse, Monoclonal |
| Biozol Catalog Number: | ABT-AH11906-U0020 |
| Supplier Catalog Number: | AH11906-U0020 |
| Alternative Catalog Number: | ABT-AH11906-U0020-20UG |
| Manufacturer: | Abcepta |
| Host: | Mouse |
| Category: | Antikörper |
| Application: | FC, IF, IHC-Fr |
| Species Reactivity: | Human |
| Alternative Names: | Mucin-5AC, MUC-5AC, Gastric mucin, Lewis B blood group antigen, LeB, Major airway glycoprotein, Mucin-5 subtype AC, tracheobronchial, Tracheobronchial mucin, TBM, MUC5AC, MUC5 |
| This MAb recognizes the peptide core of gastric mucin M1 (recently identified as Mucin 5AC).ĀIts epitope is located in the N-terminal cysteine rich part of the peptide core of MUC5AC, which is heavily glycosylated. Its epitope is destroyed by beta-mercaptoethanol but not by periodate treatment. MAb 9-13M1 pairs with MAb 1-13M1 to measure MUC5AC protein by ELISA. This mucin is present in primary ovarian mucinous cancer but usually absent in colorectal adenocarcinoma, thus showing an expression pattern opposite to MUC2. Together with a panel of antibodies, Anti-MUC5AC may be useful for differential identification of primary mucinous ovarian tumors from colon adenocarcinoma metastatic to the ovary. MUC5AC antibodies may also be useful for identification of intestinal metaplasia as well as in the identification of pancreatic carcinoma and pre-cancerous changes vs. normal pancreas. |
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