CD106 / VCAM1 (Activated Endothelial Cell Marker) Antibody - With BSA and Azide, Clone: [B-K9], Mouse, Monoclonal
Catalog Number:
ABT-AH12507-U0020
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| Article Name: | CD106 / VCAM1 (Activated Endothelial Cell Marker) Antibody - With BSA and Azide, Clone: [B-K9], Mouse, Monoclonal |
| Biozol Catalog Number: | ABT-AH12507-U0020 |
| Supplier Catalog Number: | AH12507-U0020 |
| Alternative Catalog Number: | ABT-AH12507-U0020-20UG |
| Manufacturer: | Abcepta |
| Host: | Mouse |
| Category: | Antikörper |
| Application: | FC, IF |
| Species Reactivity: | Human |
| Alternative Names: | Vascular cell adhesion protein 1, V-CAM 1, VCAM-1, INCAM-100, CD106, VCAM1, L1CAM |
| Recognizes a protein of 110kDa, identified as CD106 (also known as vascular cell adhesion molecule-1 (VCAM-1) and INCAM-100). CD106 is a member of the Ig superfamily of adhesion molecules and is expressed at high levels on cytokine stimulated vascular endothelial cells, and at minimal levels on un-stimulated endothelial cells. It is also present on follicular and inter-follicular dendritic cells of lymph nodes, myoblasts, and some macrophages. CD106 serves as a ligand for leukocyte integrin (VLA-4 or CD49d/CD29) and mediates cell adhesion of leukocytes to activated endothelium. It plays a role in various immunological and inflammatory responses. This MAb inhibits the binding of leukocytes to VCAM-1 on stimulated endothelial cells. |
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