CD1b (T-Cell Surface Glycoprotein) Antibody - With BSA and Azide, Clone: [100-1A5], Mouse, Monoclonal
Catalog Number:
ABT-AH12589-U0020
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| Article Name: | CD1b (T-Cell Surface Glycoprotein) Antibody - With BSA and Azide, Clone: [100-1A5], Mouse, Monoclonal |
| Biozol Catalog Number: | ABT-AH12589-U0020 |
| Supplier Catalog Number: | AH12589-U0020 |
| Alternative Catalog Number: | ABT-AH12589-U0020-20UG |
| Manufacturer: | Abcepta |
| Host: | Mouse |
| Category: | Antikörper |
| Application: | FC, IF |
| Species Reactivity: | Human |
| Alternative Names: | T-cell surface glycoprotein CD1b, CD1b, CD1B |
| The mouse monoclonal antibody recognizes CD1b, a 44kDa type I glycoprotein associated with beta2-microglobulin (Workshop IV, Code T015). It is expressed on dendritic cells, Langerhans cells, thymocytes, and T acute lymphoblastic leukemia cells. The CD1 multigene family encodes five forms of the CD1 T-cell surface glycoprotein in human, designated CD1A, 1B, 1C, 1D and 1E. CD1, a type 1 membrane protein, has structural similarity to the MHC class I antigen and has been shown to present lipid antigens for recognition by T lymphocytes. Constitutive endocytosis of CD1B molecules and the differential sorting of MHC class II from lysosomes separate peptide- and lipid antigen-presenting molecules during dendritic cell maturation. CD1B is also expressed in interdigitating cells. |
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