CD6 Antibody - With BSA and Azide, Clone: [SPV-L14], Mouse, Monoclonal
Catalog Number:
ABT-AH12620-U0020
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| Article Name: | CD6 Antibody - With BSA and Azide, Clone: [SPV-L14], Mouse, Monoclonal |
| Biozol Catalog Number: | ABT-AH12620-U0020 |
| Supplier Catalog Number: | AH12620-U0020 |
| Alternative Catalog Number: | ABT-AH12620-U0020-20UG |
| Manufacturer: | Abcepta |
| Host: | Mouse |
| Category: | Antikörper |
| Application: | FC, IF |
| Species Reactivity: | Human, Mouse |
| Alternative Names: | T-cell differentiation antigen CD6, T12, TP120, CD6, CD6 |
| CD6 is a type I transmembrane glycoprotein that contains a 24-amino acid signal sequence, three extracellular scavenger receptor cysteine-rich (SRCR) domains, a membrane-spanning domain and a 44-amino acid cytoplasmic domain. The CD6 glycoprotein is tyrosine phosphorylated during TCR-mediated T cell activation. CD6 shows significant homology to CD5. CD6 is present on mature thymocytes, peripheral T cells and a subset of B cells. Antibodies to CD6 are used to deplete T cells from bone marrow transplants to prevent graft versus host disease. |
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