CD20 / MS4A1 (B-Cell Marker) Antibody - With BSA and Azide, Clone: [93-1B3], Mouse, Monoclonal
Catalog Number:
ABT-AH12669-U0100
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| Article Name: | CD20 / MS4A1 (B-Cell Marker) Antibody - With BSA and Azide, Clone: [93-1B3], Mouse, Monoclonal |
| Biozol Catalog Number: | ABT-AH12669-U0100 |
| Supplier Catalog Number: | AH12669-U0100 |
| Alternative Catalog Number: | ABT-AH12669-U0100-100UG |
| Manufacturer: | Abcepta |
| Host: | Mouse |
| Category: | Antikörper |
| Application: | FC, IHC |
| Species Reactivity: | Human |
| Alternative Names: | B-lymphocyte antigen CD20, B-lymphocyte surface antigen B1, Bp35, Leukocyte surface antigen Leu-16, Membrane-spanning 4-domains subfamily A member 1, CD20, MS4A1, CD20 |
| Recognizes a protein of 30-33kDa, which is identified as CD20 (Workshop V, Code CD20.4). It is a non-Ig differentiation antigen of B-cells and its expression is restricted to normal and neoplastic B-cells, being absent from all other leukocytes and tissues. CD20 is expressed by pre B-cells and persists during all stages of B-cell maturation but is lost upon terminal differentiation into plasma cells. The protein passes through the membrane 4 times with both ends in cytoplasm and exposes one short and one longer loop to the external environment. CD20 is not glycosylated in resting B-cells and its cytoplasmic domains are differentially phosphorylated upon activation. It acts as calcium channel involved in B cell activation and cell cycle progression. |
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