CD70 / TNFSF7 (Activated T- & B-Lymphocyte Marker) Antibody - With BSA and Azide, Clone: [BU69], Mouse, Monoclonal
Catalog Number:
ABT-AH12800-U0100
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| Article Name: | CD70 / TNFSF7 (Activated T- & B-Lymphocyte Marker) Antibody - With BSA and Azide, Clone: [BU69], Mouse, Monoclonal |
| Biozol Catalog Number: | ABT-AH12800-U0100 |
| Supplier Catalog Number: | AH12800-U0100 |
| Alternative Catalog Number: | ABT-AH12800-U0100-100UG |
| Manufacturer: | Abcepta |
| Host: | Mouse |
| Category: | Antikörper |
| Application: | ELISA, FC, IF, IHC-Fr, IP |
| Species Reactivity: | Human |
| Alternative Names: | CD70 antigen, CD27 ligand, CD27-L, Tumor necrosis factor ligand superfamily member 7, CD70, CD70, CD27L, CD27LG, TNFSF7 |
| It recognizes a protein of 30kDa, identified as CD70. It is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for TNFRSF27/CD27. It is a surface antigen on activated, but not on resting, T- and B-lymphocytes. It induces proliferation of co-stimulated T cells, enhances the generation of cytolytic T cells, and contributes to T cell activation. This cytokine is also reported to play a role in regulating B-cell activation, cytotoxic function of natural killer cells, and immunoglobulin synthesis. This MAb blocks the interaction between CD27 and CD70, and has been shown toĀinhibit T cell proliferation induced by dendritic cells. |
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