Anti-Luteinizing Hormone / Choriogonadotropin Receptor (LHCGR) Antibody, Clone: [LHCGR/1415], Mouse, Monoclonal

Catalog Number: ABT-AH13363-U0100
Article Name: Anti-Luteinizing Hormone / Choriogonadotropin Receptor (LHCGR) Antibody, Clone: [LHCGR/1415], Mouse, Monoclonal
Biozol Catalog Number: ABT-AH13363-U0100
Supplier Catalog Number: AH13363-U0100
Alternative Catalog Number: ABT-AH13363-U0100-100UG
Manufacturer: Abcepta
Host: Mouse
Category: Antikörper
Application: FC, IF, WB
Species Reactivity: Human
Alternative Names: Gonadotropin receptor, GTHR-II, HHG, LCGR, LGR2, LH-R, LH/CG-R, LH/CGR, LHCGR, LHR, LHRHR, LSH-R, Luteinizing hormone receptor, Luteinizing hormone/choriogonadotropin receptor, Lutropin choriogonadotropic receptor, Lutropin-choriogonadotropic hormone receptor, ULG5
Recognizes a protein of 78-85kDa, which is identified as Luteinizing hormone / choriogonadotropin receptor. Luteinizing hormone plays a role in spermatogenesis and ovulation by stimulating the testes and ovaries to produce steroids. Choriogonadotropin production in the placenta maintains estrogen and progesterone levels during the first trimester of pregnancy. Ovaries and testes abundantly express luteinizing hormone / choriogonadotropin receptor (LHCGR) as a seven transmembrane, G protein-coupled receptor glycoprotein. LHCGR influences the protective effect of pregnancy and Gonadotropin against breast cancer. The expression of LHCGR on breast carcinoma correlates in part to the degree of tumor differentiation. LHCGR -positive breast tumors occur more frequently in tumors with greater cell differentiation in premenopausal women.
Clonality: Monoclonal
Clone Designation: [LHCGR/1415]
NCBI: 3973
UniProt: P22888
Antibody Type: Monoclonal Antibody