Anti-Plakophilin-1 (PKP1) Antibody, Clone: [10B2], Mouse, Monoclonal
Catalog Number:
ABT-AH13436-U0020
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| Article Name: | Anti-Plakophilin-1 (PKP1) Antibody, Clone: [10B2], Mouse, Monoclonal |
| Biozol Catalog Number: | ABT-AH13436-U0020 |
| Supplier Catalog Number: | AH13436-U0020 |
| Alternative Catalog Number: | ABT-AH13436-U0020-20UG |
| Manufacturer: | Abcepta |
| Host: | Mouse |
| Category: | Antikörper |
| Application: | FC, IF, WB |
| Species Reactivity: | Human, Mouse |
| Alternative Names: | B6P, Band 6 protein, PKP1, Plakophilin-1 (ectodermal dysplasia/skin fragility syndrome) |
| Recognizes a protein of 75kDa, identified as Plakophilin-1. Its epitope maps between aa 1-27 human Plakophilin-1. Plakophilins 1, 2, 3 and 4 (PKP1-4) influence development and participate in linking cadherins to cytoskeletal intermediate filaments. Plakophilins 1-4 contain arm-repeat (armadillo) domains and localize to nuclei and cell desmosomes (cell-cell junctions found in suprabasal layers of stratifying epithelia that undergo mechanical stress). Plakophilin 2 is important for desmosome assembly and is an essential morphogenic factor and architectural component of the heart. |
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