SFRS1 is a member of the arginine/serine-rich splicing factor protein family, and functions in both constitutive and alternative pre-mRNA splicing. The protein binds to pre-mRNA transcripts and components of the spliceosome, and can either activate or repress splicing depending on the location of the pre-mRNA binding site. The proteins ability to activate splicing is regulated by phosphorylation and interactions with other splicing factor associated proteins.
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Target:
This SFRS1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 158-186 amino acids from the C-terminal region of human SFRS1.
Antibody Type:
Polyclonal Antibody
Western blot analysis of SFRS1 (arrow) using rabbit polyclonal SFRS1 Antibody (C-term) (Cat. AP68
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