Tolebrutinib (SAR442168) is a potent, selective, orally active and blood-brain barrier capable brutons tyrosine kinase (BTK) inhibitor with IC50 values of 0.4 and 0.7 nM in Ramos B cells and HMC microglia, respectively. Tolebrutinib has an effect on central nervous system immunity. Tolebrutinib can be used in multiple sclerosis (MS) studies.
Molecular Weight:
455.51
Purity:
>99.0%
CAS Number:
[1971920-73-6]
Formula:
C26H25N5O3
Target:
BTK
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