The immunogen is a synthetic peptide directed towards the N-terminal region of Human CBFB
Alternative Names:
PEBP2B
CBFB encodes a protein that is the beta subunit of a heterodimeric core-binding transcription factor belonging to the PEBP2/CBF transcription factor family which master-regulates a host of genes specific to hematopoiesis (e.g., RUNX1) and osteogenesis (e.g., RUNX2). The beta subunit is a non-DNA binding regulatory subunit, it allosterically enhances DNA binding by alpha subunit as the complex binds to the core site of various enhancers and promoters, including murine leukemia virus, polyomavirus enhancer, T-cell receptor enhancers and GM-CSF promoters.
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Host: Rabbit Target Name: CBFB Sample Type: Jurkat Whole Cell lysates Antibody Dilution: 1.0ug/mlCBFB is strongly supported by BioGPS gene expression data to be expressed in Human Jurkat cells