YAF2 Antibody - middle region
Catalog Number:
ASB-ARP31459_T100
- Images (3)
| Article Name: | YAF2 Antibody - middle region |
| Biozol Catalog Number: | ASB-ARP31459_T100 |
| Supplier Catalog Number: | ARP31459_T100 |
| Alternative Catalog Number: | ASB-ARP31459_T100-25UL,ASB-ARP31459_T100-100UL |
| Manufacturer: | Aviva |
| Host: | Rabbit |
| Category: | Proteine/Peptide |
| Application: | IHC, WB |
| Species Reactivity: | Bovine, Canine, Equine, Guinea pig, Human, Mouse, Rabbit, Rat |
| Immunogen: | The immunogen is a synthetic peptide directed towards the middle region of human YAF2 |
| Alternative Names: | MGC41856 |
| YAF2 interacts with YY1, a zinc finger protein involved in negative regulation of muscle-restricted genes. YAF2 contains a single N-terminal C2-X10-C2 zinc finger, and in contrast to YY1, is up-regulated during myogenic differentiation. It also facilitates proteolytic cleavage of YY1 by the calcium- activated protease, m-calpain, suggesting a mechanism by which this protein antagonizes the negative effect of YY1.The protein encoded by this gene interacts with YY1, a zinc finger protein involved in negative regulation of muscle-restricted genes. This gene product itself contains a single N-terminal C2-X10-C2 zinc finger, and in contrast to YY1, is up-regulated during myogenic differentiation. It also facilitates proteolytic cleavage of YY1 by the calcium- activated protease, m-calpain, suggesting a mechanism by which this protein antagonizes the negative effect of YY1. Multiple transcript variants encoding different isoforms have been found for this gene, but the full-length nature of only two have been confirmed to date. |
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HumanMuscle |
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WB Suggested Anti-YAF2 Antibody Titration: 1.25ug/ml ELISA Titer: 1:62500 Positive Control: Jurkat cell lysate |
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YAF2 antibody - middle region (ARP31459_T100) in Human Jurkat using Western Blot |
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